The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2023

Filed:

Jan. 31, 2019
Applicant:

West China Hospital, Sichuan University, Sichuan, CN;

Inventors:

Jin Liu, Sichuan, CN;

Bowen Ke, Sichuan, CN;

Wensheng Zhang, Sichuan, CN;

Jun Yang, Sichuan, CN;

Lei Tang, Sichuan, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/02 (2006.01); C07D 211/60 (2006.01); C07C 231/12 (2006.01); C07C 237/04 (2006.01); C07D 205/04 (2006.01); C07D 207/16 (2006.01); C07D 223/06 (2006.01); C07D 225/02 (2006.01);
U.S. Cl.
CPC ...
C07D 211/60 (2013.01); C07C 231/12 (2013.01); C07C 237/04 (2013.01); C07D 205/04 (2013.01); C07D 207/16 (2013.01); C07D 223/06 (2013.01); C07D 225/02 (2013.01);
Abstract

A compound is shown in formula I and can be in the form of a pharmaceutically acceptable salt, or a stereoisomer, or a solvate, or a prodrug, or a metabolite. The compound takes effect rapidly and has a long-time local anesthetic effect following a single dose, with the sensory nerve blocking time being greater than the motor nerve blocking time, has both a long-acting local anesthetic effect and a selective local anesthetic effect, significantly reduces side effects of the compositions QX314 and QX314 and a quaternary ammonium salt compound with surfactant structural characteristics, and is safer. The compound of formula I of the present invention and a pharmaceutically acceptable salt thereof can be used for preparing drugs that have a long-time local anesthetic effect and a selective local anesthetic effect.


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