The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2023

Filed:

Jan. 22, 2021
Applicants:

The Usa, As Represented BY the Secretary, Dept. of Health and Human Services, Bethesda, MD (US);

Unm Rainforest Innovations, Albuquerque, NM (US);

Inventors:

Alan Remaley, Bethesda, MD (US);

John T. Schiller, Kensington, MD (US);

Marcelo Amar, Gaithersburg, MD (US);

Bryce Chackerian, Albuquerque, NM (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/005 (2006.01); A61P 9/10 (2006.01); C07K 9/00 (2006.01); C07K 11/00 (2006.01); A61K 39/00 (2006.01); A61K 38/10 (2006.01); C12N 9/64 (2006.01); A61K 47/69 (2017.01); A61K 45/06 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0005 (2013.01); A61K 38/10 (2013.01); A61K 45/06 (2013.01); A61K 47/6901 (2017.08); A61P 9/10 (2018.01); C12N 9/6454 (2013.01); C12Y 304/21061 (2013.01); A61K 2039/60 (2013.01); A61K 2039/627 (2013.01); C07K 9/00 (2013.01); C07K 11/00 (2013.01); C07K 14/47 (2013.01); C12N 2795/18123 (2013.01); C12N 2795/18134 (2013.01); C12N 2795/18141 (2013.01);
Abstract

A vaccine construct comprising an antigenic PCSK9 peptide and an immunogenic carrier, and methods of using the same that are effective to lower blood cholesterol levels in a mammal and treat dyslipidemias and related disease states in a mammal without the frequency of administration required by passive immunity strategies.


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