The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2023

Filed:

Sep. 20, 2018
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Kyriacos A. Athanasiou, Irvine, CA (US);

Jerry C. Hu, Irvine, CA (US);

Heenam Kwon, Irvine, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/32 (2015.01); C12N 5/077 (2010.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/32 (2013.01); C12N 5/0068 (2013.01); C12N 5/0655 (2013.01); C12N 2509/00 (2013.01); C12N 2509/10 (2013.01); C12N 2513/00 (2013.01); C12N 2521/00 (2013.01); C12N 2527/00 (2013.01);
Abstract

The methods described herein are for conserving highly expanded cells that have functional properties such as potential for use in neotissue constructs. For example, highly expanded chondrocytes that can be used to construct neocartilage exhibiting functional properties similar to native articular cartilage. The methods and systems feature processes that form functional, human cartilage using cells that have been expanded to at least 1.5×10times or P3 or greater. This enables a large quantity of engineered cartilage implants to be produced from few cells.


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