The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2023

Filed:

Aug. 24, 2020
Applicant:

Glycom A/s, Hørsholm, DK;

Inventors:

Louise Kristine Vigsnæs, Copenhagen, DK;

Bruce McConnell, La Tour de Peilz, CH;

Assignee:

GLYCOM A/S, Hørsholm, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/702 (2006.01); A61P 3/04 (2006.01); A61P 3/10 (2006.01); A61P 1/00 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/702 (2013.01); A61K 9/0053 (2013.01); A61P 1/00 (2018.01); A61P 3/04 (2018.01); A61P 3/10 (2018.01);
Abstract

A human milk oligosaccharide (HMO) or a synthetic composition comprising said HMO, for use in increasing the abundance, particularly the relative abundance, of aof thephylogenic group in the microbiota in the gastro-intestinal tract of a human, preferably a non-infant human. The HMO(s) and/or synthetic composition is useful in; increasing particularly the relative abundance ofand/or; for treating or preventing in said non-infant human with type 2 diabetes and/or obesity; an enteropathogenic infection; impaired gut barrier function and/or; an inflammation related to gastro¬intestinal condition, preferably irritable bowel disease (IBD) or irritable bowel syndrome (IBS); as a nutritional composition. The HMO is a fucosylated neutral HMO, a non-fucosylated neutral HMO, or a mixture of a fucosylated and a non-fucosylated neutral HMO. The HMOs comprises 2'-fucosyllactose (preferred), 2′-fucosyllactose (preferred), 3-fucosyllactose, difucosyllactose (preferred), lacto-N-fucopentaose, fucosyl-lacto-N-hexaose, fucosyl-para-lacto-N-hexaose, lacto-N-tetraose (preferred), lacto-N-neotetraose (preferred), lacto-N-hexaose, lacto-N-neohexaose, para-lacto-N-hexaose and para-lacto-N-neohexaose.


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