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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11696890 B1

PDFFull Text
Date of Patent:
Jul. 11, 2023

Filed:

Dec. 02, 2019

Tumescent infiltration drug delivery of high subcutaneous drug concentrations with prolonged local and systemic effects and minimal local or systemic toxicity

Applicant:

HK Pharma, San Clemente, CA (US);

Inventors:

Jeffrey Alan Klein, San Juan Capistrano, CA (US);

Paytra Alan Klein, Newport Beach, CA (US);

Assignee:

HK PHARMA, San Clemente, CA (US);

Attorney:

Knobbe, Martens, Olson & Bear, LLP

Primary Examiner:

Sarah Pihonak

Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 31/137 (2006.01); A61K 9/08 (2006.01); A61K 45/06 (2006.01); A61K 31/56 (2006.01); A61K 31/167 (2006.01); A61K 31/522 (2006.01); A61K 31/546 (2006.01); A61K 31/52 (2006.01); A61K 31/4164 (2006.01); A61K 47/02 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 31/137 (2013.01); A61K 31/167 (2013.01); A61K 31/4164 (2013.01); A61K 31/52 (2013.01); A61K 31/522 (2013.01); A61K 31/546 (2013.01); A61K 45/06 (2013.01); A61K 47/02 (2013.01); A61K 31/56 (2013.01);
Abstract

A tumescent composition comprising a drug or a therapeutic agent in a tumescent solution, wherein a tumescent concentration of the drug or therapeutic agent is simultaneously below a threshold for local, subcutaneous tissue toxicity, above a threshold for positive local therapeutic effect, and above a concentration safely achievable by intravenous (IV), intramuscular (IM) or oral (PO) delivery; and the tumescent solution comprises a vasoconstrictor; a pharmaceutically acceptable carrier; and optionally a local anesthetic, wherein the tumescent solution does not comprise an antibiotic.

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