The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2023

Filed:

Dec. 01, 2020
Applicant:

Cerno Bioscience Llc, Las Vegas, NV (US);

Inventor:

Yongdong Wang, Las Vegas, NV (US);

Assignee:

CERNO BIOSCIENCE LLC, Las Vegas, NV (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
H01J 49/36 (2006.01); H01J 49/00 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
H01J 49/0036 (2013.01); G01N 33/6848 (2013.01); H01J 49/0009 (2013.01);
Abstract

A method for mass spectral analysis of molecules based on full mass spectral profile or raw scan mode data, comprising the steps of specifying the basic building blocks for the molecule; estimating initial values including trial numbers of building blocks, charge states, and possible modifications; calculating discrete isotope distributions based on elemental compositions; calculating a profile mode theoretical mass spectrum using a target mass spectrum peak shape function; performing regression analysis between acquired profile mode mass spectrum data and calculated theoretical mass spectrum data and reporting regression statistics; using regression statistics as feedbacks to update initially estimated values including trial numbers of building blocks, charge states, and possible modifications; and repeating selected step to optimize the regression statistics. A mass spectrometer operating in accordance with the method. A medium having computer readable program instructions for causing a mass spectrometer associated with a computer to operate in accordance with the method.


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