The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2023

Filed:

Jan. 23, 2017
Applicant:

Otraces, Inc., Rockville, MD (US);

Inventors:

Yuriy Fuksenko, Derwood, MD (US);

Richard Saul, Gaithersburg, MD (US);

Galina Krasik, Montgomery Village, MD (US);

Mohsen Marefat, Silver Spring, MD (US);

Keith Lingenfelter, Potomac, MD (US);

Assignee:

Otraces Inc., Rockville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16H 50/20 (2018.01); G16B 5/00 (2019.01); G16H 50/30 (2018.01); G16B 5/20 (2019.01); G16H 50/50 (2018.01);
U.S. Cl.
CPC ...
G16H 50/20 (2018.01); G16B 5/00 (2019.02); G16B 5/20 (2019.02); G16H 50/30 (2018.01); G16H 50/50 (2018.01); Y02A 90/10 (2018.01);
Abstract

The present invention relates to systems and methods for improving the accuracy of disease diagnosis and to associated diagnostic tests involving the correlation of measured analytes with binary outcomes (e.g., not-disease or disease), as well as higher-order outcomes (e.g., one of several phases of a disease). Methods of the present invention use biomarker sets, preferably those with orthogonal functionality, to obtain concentration and proximity score values for disease and non-disease states. The biomarker set's proximity scores are graphed on an orthogonal grid, with one dimension for each biomarker. The proximity scores and orthogonal gridding is then used to calculate a disease state or non-disease state diagnosis for the patient.


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