The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2023
Filed:
Jan. 10, 2018
Applicant:
Precigen, Inc., Germantown, MD (US);
Inventors:
Rutul R. Shah, Blacksburg, VA (US);
Thomas D. Reed, Blacksburg, VA (US);
Cheryl G. Bolinger, Blacksburg, VA (US);
Assignee:
PRECIGEN, INC., Germantown, MD (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/63 (2006.01); G01N 33/68 (2006.01); C12N 15/10 (2006.01); C07K 14/54 (2006.01); C07K 14/725 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 15/635 (2013.01); C07K 14/5443 (2013.01); C07K 14/7051 (2013.01); C12N 15/1055 (2013.01); C12N 15/63 (2013.01); C12N 15/85 (2013.01); G01N 33/6845 (2013.01); C07K 2319/80 (2013.01); C12N 2800/90 (2013.01);
Abstract
Disclosed herein are polynucleotides encoding ligand-inducible gene switch polypeptides, and systems comprising gene switch polypeptides for modulating the expression of a heterologous gene and an interleukin in a host cell. The compositions, methods and systems described herein facilitate ligand dependent expression of polypeptides including but not limited to cytokines and antigen binding polypeptides.