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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11692044 B1

PDFFull Text
Date of Patent:
Jul. 04, 2023

Filed:

Apr. 14, 2017

Compositions and methods for the treatment of systemic inflammatory response syndromes

Applicant:

Wisconsin Alumni Research Foundation, Madison, WI (US);

Inventors:

Jordan Marshall Sand, Madison, WI (US);

Mark Eric Cook, Madison, WI (US);

Daniel Elmer Butz, Madison, WI (US);

Assignee:

WISCONSIN ALUMNI RESEARCH FOUNDATION, Madison, WI (US);

Attorney:

Cantor Colburn LLP

Primary Examiner:

Sharon X Wen

Int. Cl.
CPC ...
C07K 16/40 (2006.01); C07K 5/113 (2006.01); C12N 9/20 (2006.01); A23K 20/147 (2016.01); A23L 33/17 (2016.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A23K 20/147 (2016.05); A23L 33/17 (2016.08); C07K 5/1021 (2013.01); C12N 9/20 (2013.01); C12Y 301/01004 (2013.01); A23V 2002/00 (2013.01); A61K 2039/505 (2013.01); C07K 2317/11 (2013.01); C07K 2317/23 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01);
Abstract

Described herein are peptides from secretory phospholipase A-IB and antibodies that can be used to reduce the contribution of the gastrointestinal tract to inflammatory processes including systemic inflammatory responses. Specifically, antibodies that bind specifically a peptide from secretory phospholipase A-IB prevent death in a mouse model of LPS-induced endotoxemia. The antibodies described herein are particularly useful to treat systemic inflammatory response syndromes, including sepsis.

Find Patent Forward Citations

Sand, Jordan. (2023). Compositions and methods for the treatment of systemic inflammatory response syndromes (U.S. Patent No. 11692044). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11692044

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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