The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2023
Filed:
Feb. 02, 2019
Applicant:
Adagene Inc., Grand Cayman, KY;
Inventors:
Peter Peizhi Luo, San Mateo, CA (US);
Fangyong Du, Jiangsu, CN;
Zhongzong Pan, Jiangsu, CN;
Guizhong Liu, Jiangsu, CN;
Assignee:
Adagene Inc., Grand Cayman, KY;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/00 (2006.01); C12N 5/10 (2006.01); A61K 31/713 (2006.01); C12N 15/63 (2006.01); A61P 35/00 (2006.01); C12N 5/0783 (2010.01); C12N 5/071 (2010.01); G01N 33/574 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2818 (2013.01); A61K 31/713 (2013.01); A61P 35/00 (2018.01); C07K 16/2809 (2013.01); C12N 5/0638 (2013.01); C12N 5/0682 (2013.01); C12N 5/10 (2013.01); C12N 15/63 (2013.01); G01N 33/574 (2013.01); A61K 45/06 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/51 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/622 (2013.01); C07K 2317/70 (2013.01); C07K 2317/732 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); C07K 2319/30 (2013.01); C07K 2319/50 (2013.01); C07K 2319/70 (2013.01);
Abstract
Provided herein are cross-reactive antibodies (or antigen binding fragments thereof) that bind to human CTLA4, activatable antibodies that bind to human CTLA4, nucleic acid molecules encoding the same, pharmaceutical compositions thereof, and methods of their therapeutic use (e.g., for treatment of cancer).