The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2023

Filed:

May. 17, 2021
Applicant:

Elasmogen Limited, Aberdeen, GB;

Inventors:

Caroline Barelle, Aberdeen, GB;

Mischa Roland Muller, Zurich-Schlieren, CH;

Valerie Calabro, Carro, FR;

Jack Bikker, Union Beach, NJ (US);

John Steven, Aberdeen, GB;

Lioudmila Tchistiakova, Cambridge, MA (US);

Oleg Kovalenko, Cambridge, MA (US);

Andrea Olland, Arlington, MA (US);

Assignee:

ELASMOGEN LIMITED, Aberdeen, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); C07K 16/28 (2006.01); C07K 16/46 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); C07K 16/2827 (2013.01); C07K 16/46 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/569 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); C07K 2319/30 (2013.01); C07K 2319/31 (2013.01);
Abstract

The present invention provides a single domain specific binding molecule having the structureFW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4in which the Framework Regions FW1, FW2, FW3a, FW3b, and FW4, the Complementarity Determining Regions CDR1 and CDR3, and the Hypervariable Regions HV2, and HV4 have amino acid sequences as defined which provide a high affinity anti-human serum albumin (HSA) binding domain.


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