The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2023

Filed:

Sep. 20, 2019
Applicant:

University of Kentucky Research Foundation, Lexington, KY (US);

Inventors:

Jurgen Rohr, Lexington, KY (US);

Oleg Tsodikov, Lexington, KY (US);

Markos Leggas, Lexington, KY (US);

Caixia Hou, Lexington, KY (US);

Joseph Eckenrode, Lexington, TN (US);

Prithiba Mitra, Lexington, KY (US);

Abhisek Mandal, Lexington, KY (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 15/24 (2006.01);
U.S. Cl.
CPC ...
C07H 15/24 (2013.01);
Abstract

Mithramycin (MTM) short side chain ketone (SK) derivatives and MTM short side chain diketone (SDK) derivatives are provided. The MTM SK and MTM SDK derivatives are useful for treatment of cancer or neuro-diseases associated with an aberrant erythroblast transformation-specific transcription factor. Unique MTM SK and MTM SDK derivatives have increased selectively toward ETS transcription factor.


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