The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2023

Filed:

Dec. 20, 2018
Applicant:

Otago Innovation Limited, Dunedin, NZ;

Inventors:

Margaret Anne Brimble, Auckland, NZ;

Greg Murray Cook, Dunedin, NZ;

Scott Andrew Ferguson, Dunedin, NZ;

Adam Heikal, Kolsås, NZ;

David Rennison, Auckland, NZ;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/40 (2006.01); C07D 401/12 (2006.01); A61K 45/06 (2006.01); C07D 401/14 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 215/40 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); A61K 45/06 (2013.01);
Abstract

The invention provides novel quinoline sulfonamide compounds of Formula I: and their use for the treatment or prevention of bacterial infections caused by both Gram positive and Gram negative bacteria such as, for example, infections caused by one or more bacteria from the Enterobactericeae, Staphylococcaceae, or Streptococcaceae families. The compounds described and claimed herein may be formulated in one or more pharmaceutical or veterinary compositions for use in animal husbandry, and in particular in relation to the treatment of mastitis by directly targeting mastitis causing bacteria in a bovine herd. In certain embodiments described herein the pharmaceutical or veterinary compositions are formulated as a spray for direct administration to the udder of the bovine animal such as a cow.


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