The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2023
Filed:
Feb. 06, 2020
Applicant:
Cognition Therapeutics, Inc., Pittsburgh, PA (US);
Inventors:
Gilbert M. Rishton, Los Angeles, CA (US);
Susan M. Catalano, Pittsburgh, PA (US);
Gary C. Look, Santa Clara, CA (US);
Assignee:
Cognition Therapeutics, Inc., Pittsburgh, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/44 (2006.01); C07D 209/62 (2006.01); C07D 403/06 (2006.01); C07D 491/048 (2006.01); C07D 491/056 (2006.01); A61K 31/4035 (2006.01); A61K 31/404 (2006.01); A61K 31/407 (2006.01); A61K 31/496 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
C07D 209/44 (2013.01); A61K 31/4035 (2013.01); A61P 25/00 (2018.01); C07D 209/62 (2013.01); C07D 403/06 (2013.01); C07D 491/048 (2013.01); C07D 491/056 (2013.01);
Abstract
Isoindoline sigma-2 receptor antagonist compounds, pharmaceutical compositions comprising such compounds, and methods for inhibiting Abeta-associated synapse loss or synaptic dysfunction in neuronal cells, modulating an Abeta-associated membrane trafficking change in neuronal cells, and treating cognitive decline associated with Abeta pathology are provided.