logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11690898 B1

PDFFull Text
Date of Patent:
Jul. 04, 2023

Filed:

Nov. 06, 2019

Adeno-associated virus factor viii vectors, associated viral particles and therapeutic formulations comprising the same

Applicant:

Biomarin Pharmaceutical Inc., Novato, CA (US);

Inventors:

Stuart Bunting, Novato, CA (US);

Peter Cameron Colosi, Novato, CA (US);

Erno Pungor, Novato, CA (US);

Assignee:

BIOMARIN PHARMACEUTICAL INC., Novato, CA (US);

Attorney:

Marshall, Gerstein & Borun LLP

Primary Examiner:

Maria Marvich

Int. Cl.
CPC ...
C12N 15/864 (2006.01); A61K 38/37 (2006.01); A61K 48/00 (2006.01); A61K 47/10 (2017.01); A61K 47/26 (2006.01); A61K 39/12 (2006.01); C07K 14/755 (2006.01); A61K 47/02 (2006.01); C12N 7/00 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
A61K 38/37 (2013.01); A61K 39/12 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/26 (2013.01); A61K 48/0008 (2013.01); A61K 48/0075 (2013.01); C07K 14/755 (2013.01); C12N 7/00 (2013.01); G01N 33/6854 (2013.01); C12N 2710/16044 (2013.01); C12N 2750/14121 (2013.01); C12N 2750/14141 (2013.01); C12N 2750/14143 (2013.01); G01N 2333/015 (2013.01);
Abstract

The invention provides adeno-associated virus (AAV) Factor VIII (FVIII)-encoding/expressing vectors and virus, including AAV FVIII vectors with high expression activity and AAV FVIII vectors that express full-length or truncated functional FVIII protein. The invention also relates to methods of making the herein described AAV FVIII vectors, recombinant AAV FVIII virus particles comprising or expressing such vectors, associated pharmaceutical formulations comprising the same and therapeutic uses thereof.

Find Patent Forward Citations

Bunting, Stuart. (2023). Adeno-associated virus factor viii vectors, associated viral particles and therapeutic formulations comprising the same (U.S. Patent No. 11690898). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11690898

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…