The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2023
Filed:
Nov. 26, 2018
Immatics Us, Inc., Houston, TX (US);
Monique Dao, Houston, TX (US);
Steffen Walter, Houston, TX (US);
Melinda Mata, Houston, TX (US);
Aleksandra Nowicka, Houston, TX (US);
Yannick Bulliard, Houston, TX (US);
Sarah Missell, Tuebingen, DE;
Sabrina Kuttruff-Coqui, Filderstadt-Sielmingen, DE;
Norbert Hilf, Kirchentellinsfurt, DE;
IMMATICS US, INC., Houston, TX (US);
Abstract
The present disclosure relates to expansion and activation of T cells. In an aspect, the present disclosure relates to expansion and activation of γδ T cells that may be used for transgene expression. In another aspect, the disclosure relates to expansion and activation of γδ T cells while depleting α- and/or β-TCR positive cells. T cell populations comprising expanded γδ T cell and depleted or reduced α- and/or β-TCR positive cells are also provided for by the instant disclosure. The disclosure further provides for methods of using the disclosed T cell populations.