The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2023
Filed:
Nov. 07, 2017
Cyclerion Therapeutics, Inc., Cambridge, MA (US);
Joon Jung, Newton, MA (US);
Thomas Wai-Ho Lee, Lexington, MA (US);
Rajesh R. Iyengar, West Newton, MA (US);
Nicholas Robert Perl, Somerville, MA (US);
Peter Germano, Newton, MA (US);
Maria D. Ribadeneira, Cambridge, MA (US);
Kim Tang, Belmont, MA (US);
Cyclerion Therapeutics, Inc., Cambridge, MA (US);
Abstract
The present disclosure relates to the use of stimulators of soluble guanylate cyclase (sGC), pharmaceutically acceptable salts thereof and pharmaceutical formulations or dosage forms comprising them, alone or in combination with one or more additional agents, for the treatment of various CNS diseases, wherein an increase in sGC stimulation, or an increase in the concentration of nitric oxide (NO), or cyclic guanosine 3',5′-monophosphate (cGMP) or both, or an upregulation of the NO pathway is desirable.