The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2023
Filed:
Mar. 08, 2017
Applicants:
Board of Regents, the University of Texas System, Austin, TX (US);
New York Medical College, Valhalla, NY (US);
Inventors:
John R. Falck, Austin, TX (US);
Michal L. Schwartzman, Valhalla, NY (US);
Victor Garcia, Valhalla, NY (US);
Assignees:
Board of Regents, The University of Texas System, Austin, TX (US);
New York Medical College, Valhalla, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/201 (2006.01); C07C 59/42 (2006.01); A61K 31/41 (2006.01); A61K 47/54 (2017.01); A61P 13/12 (2006.01); A61K 31/197 (2006.01); C07C 233/49 (2006.01); C07C 247/12 (2006.01); C07D 257/06 (2006.01); C40B 40/04 (2006.01); C07K 14/72 (2006.01); C40B 30/04 (2006.01); G01N 33/92 (2006.01); C07D 257/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/41 (2013.01); A61K 31/197 (2013.01); A61K 31/201 (2013.01); A61K 47/542 (2017.08); A61P 13/12 (2018.01); C07C 59/42 (2013.01); C07C 233/49 (2013.01); C07C 247/12 (2013.01); C07D 257/04 (2013.01); C07D 257/06 (2013.01); C07K 14/723 (2013.01); C40B 30/04 (2013.01); C40B 40/04 (2013.01); G01N 33/92 (2013.01); G01N 2333/705 (2013.01); G01N 2500/00 (2013.01);
Abstract
The present invention concerns compounds and their use to treat cardiovascular disease, renal disease, thrombic disease, stroke, metabolic syndrome, cell proliferation, and ischemic cardiovascular disorders. Compounds of the present invention display significant potency as antagonists of 20-hydroxyeicosatetraenoic acid (20-HETE), and function as anti-hypertensive, anti-inflammatory, or anti-growth agents.