The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2023

Filed:

May. 20, 2019
Applicant:

Celanese Eva Performance Polymers Corporation, Irving, TX (US);

Inventor:

Christian Schneider, Hattersheim, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 49/04 (2006.01); A61K 38/47 (2006.01); A61K 38/39 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5026 (2013.01); A61K 9/5031 (2013.01); A61K 9/5073 (2013.01); A61K 9/5089 (2013.01); A61K 38/39 (2013.01); A61K 38/47 (2013.01); A61K 49/04 (2013.01); C12Y 304/22032 (2013.01); C12Y 304/22033 (2013.01);
Abstract

An implantable device for delivery of a macromolecular drug compound is provided. The device comprises a core having an outer surface and a membrane layer positioned adjacent to the outer surface of the core. The core comprises a core polymer matrix within which is dispersed a drug compound having a molecular weight of about 0.5 kDa or more, the polymer matrix containing a hydrophobic polymer. Further, the membrane layer comprises a membrane polymer matrix within which the macromolecular drug compound is optionally dispersed. The membrane polymer matrix contains a hydrophobic polymer in combination with a hydrophilic compound, and the weight ratio of the hydrophobic polymer to the hydrophilic compound within the membrane polymer matrix ranges from about 0.25 to about 200.


Find Patent Forward Citations

Loading…