The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2023

Filed:

Jun. 30, 2020
Applicant:

Nuralogix Corporation, Toronto, CA;

Inventors:

Kang Lee, Toronto, CA;

Andrew Barszczyk, Woodbridge, CA;

Sijia Wu, Newmarket, CA;

Yousef Yasin, Toronto, CA;

Winston De Armas, Toronto, CA;

Alan Ding, North Vancouver, CA;

Assignee:

NURALOGIX CORPORATION, Toronto, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/1455 (2006.01); G06N 20/20 (2019.01); G06N 20/10 (2019.01); A61B 5/145 (2006.01);
U.S. Cl.
CPC ...
A61B 5/1455 (2013.01); A61B 5/14532 (2013.01); A61B 5/14551 (2013.01); G06N 20/10 (2019.01); G06N 20/20 (2019.01);
Abstract

Provided are systems and methods for determination of a concentration of one or more blood biomarkers of a human subject. The method including: determining, using a first machine learning model trained with a hemoglobin concentration (HC) changes training set, bit values from a set of bitplanes in a captured image sequence that represent the HC changes of the subject, the set of bitplanes being those that are determined to approximately maximize a signal-to-noise ratio (SNR), the HC changes training set including bit values from each bitplane of images captured from a set of subjects for which HC changes are known; determining, using a second machine learning model trained using a blood biomarkers training set, concentration of one or more blood biomarkers, the blood biomarkers training set including previously determined HC change signals from other subjects and one or more blood panels from those subjects as ground truth data.


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