The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 27, 2023

Filed:

Dec. 27, 2017
Applicant:

GE Healthcare Bio-sciences Ab, Uppsala, SE;

Inventors:

Ola Lind, Uppsala, SE;

Johan Fredrik Avallin, Uppsala, SE;

Andreas Torbjorn Lundin, Uppsala, SE;

Nils Norrman, Uppsala, SE;

Ronnie Palmgren, Uppsala, SE;

Gustav Jose Rodrigo, Uppsala, SE;

Assignee:

Cytiva Sweden AB, Uppsala, SE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); C12M 3/00 (2006.01); C12M 3/06 (2006.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01); C12N 13/00 (2006.01); B01D 21/00 (2006.01); B03C 5/00 (2006.01); B03C 5/02 (2006.01); B03C 1/30 (2006.01); B03C 1/28 (2006.01); B03C 1/01 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54326 (2013.01); B01D 21/0009 (2013.01); B03C 1/30 (2013.01); B03C 5/00 (2013.01); B03C 5/02 (2013.01); C12M 23/48 (2013.01); C12M 27/16 (2013.01); C12M 29/00 (2013.01); C12M 41/44 (2013.01); C12M 45/07 (2013.01); C12M 47/04 (2013.01); C12M 47/10 (2013.01); C12N 13/00 (2013.01); G01N 33/5436 (2013.01); B03C 1/01 (2013.01); B03C 1/288 (2013.01); B03C 2201/26 (2013.01); G01N 2333/31 (2013.01);
Abstract

A separation system, a method in a separation system and an elution arrangement to be provided in a separation system for separating a biomolecule from a cell culture are provided. The method comprises the steps of: —providing a feed from a cell culture () comprising said biomolecule to a magnetic separator () and providing to the magnetic separator magnetic beads comprising ligands capable of binding this biomolecule; —separating by the magnetic separator said magnetic beads with bound biomolecules from the rest of the feed; —forwarding said magnetic beads as a slurry with an added buffer to an elution cell (); —eluting the bound biomolecules in the elution cell.


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