The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2023
Filed:
Sep. 21, 2018
Applicant:
Nanofaentech Co., Ltd., Gimhae-si, KR;
Inventors:
Jong-Young Kwak, Suwon-si, KR;
Min Gyu Song, Tongyeong-si, KR;
So Hee Kim, Seoul, KR;
Min Ho Choi, Seoul, KR;
Assignee:
NANOFAENTECH CO., LTD., Gimhae-si, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); C12N 5/00 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0671 (2013.01); C12N 5/0062 (2013.01); C12N 5/0068 (2013.01); G01N 33/5008 (2013.01); G01N 33/5091 (2013.01); C12N 2533/30 (2013.01); C12N 2533/40 (2013.01); C12N 2533/70 (2013.01);
Abstract
Disclosed is a nanofiber-based long-term primary hepatocyte culture system and a culture method, wherein the primary hepatocyte culture system has an advantage that it can culture cells in three-dimensions in vitro to maintain the original physiological activity of low proliferative primary hepatocytes for a long time by co-culturing indirectly by separating primary hepatocytes and hepatic non-parenchymal cells with a support consisting of nanofibers therebetween without direct co-culture.