The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 27, 2023

Filed:

Apr. 29, 2016
Applicants:

Abcheck S.r.o., Plzen, CZ;

Charles River Laboratories, Inc., Wilmington, MA (US);

Inventors:

Jacob E. Gunn Glanville, San Francisco, CA (US);

Vera Molkenthin, Tännesberg, DE;

Remko Albert Griep, Plzen, CZ;

Ahmad Trad, Plzen, CZ;

Peter Milovnik, Plzen, CZ;

Volker Lang, Wolnzach, DE;

Assignees:

ABCHECK s.r.o., Plzen, CZ;

CHARLES RIVER LABORATORIES, INC., Wilmington, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/06 (2006.01); C07K 16/46 (2006.01); C07K 16/00 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
C07K 16/005 (2013.01); C07K 16/40 (2013.01); C07K 2317/24 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/622 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present invention relates to a method for producing a population of 20 or more nucleic acids, each encoding at least one protein comprising at least one immunoglobulin variable domain having a rabbit-derived CDR3 amino acid sequence embedded in essentially human framework sequences, as well as to a population of nucleic acids and a population of proteins relates thereto and uses thereof.


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