The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2023
Filed:
Jul. 19, 2019
Applicant:
Bioverativ Therapeutics Inc., Waltham, MA (US);
Inventor:
John Kulman, Belmont, MA (US);
Assignee:
BIOVERATIV THERAPEUTICS INC., Waltham, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/755 (2006.01); C07K 14/59 (2006.01); C07K 14/79 (2006.01); A61K 38/37 (2006.01); A61K 35/14 (2015.01); C07K 14/00 (2006.01); C07K 14/435 (2006.01); C07K 14/705 (2006.01); C07K 14/76 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/755 (2013.01); A61K 35/14 (2013.01); A61K 38/37 (2013.01); C07K 14/00 (2013.01); C07K 14/43504 (2013.01); C07K 14/59 (2013.01); C07K 14/705 (2013.01); C07K 14/76 (2013.01); C07K 14/79 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/30 (2013.01); C07K 2319/31 (2013.01); C07K 2319/60 (2013.01); Y02A 50/30 (2018.01);
Abstract
Provided are recombinant Factor VIII proteins, e.g., human Factor VIII proteins with heterologous moieties inserted into flexible permissive loops located in the Factor VIII A domains, while retaining the procoagulant activity of Factor VIII.