The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2023
Filed:
Apr. 18, 2019
Amgen Inc., Thousand Oaks, CA (US);
Jeonghoon Sun, Poway, CA (US);
Lei-Ting Tony Tam, Thousand Oaks, CA (US);
Mark Leo Michaels, Encino, CA (US);
Thomas Charles Boone, Newbury Park, CA (US);
Rohini Deshpande, Camarillo, CA (US);
Yue-Sheng Li, Cambridge, MA (US);
Huiquan Han, Thousand Oaks, CA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
The present invention provides stabilized activin IIB receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the stabilized polypeptides and proteins. Compositions and methods for treating muscle-wasting diseases and metabolic disorders are also provided.