The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2023
Filed:
Dec. 17, 2018
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Brian M. Andresen, Sharon, MA (US);
Frank Bennett, Cranford, NJ (US);
Wonsuk Chang, Princeton, NJ (US);
Matthew Lloyd Childers, Medfield, MA (US);
Jared N. Cumming, Winchester, MA (US);
Jongwon Lim, Lexington, MA (US);
Min LU, Brookline, MA (US);
Benjamin Wesley Trotter, Medfield, MA (US);
Wen-lian Wu, Green Brook, NJ (US);
Brian M. Andresen, Sharon, MA (US);
Frank Bennett, Cranford, NJ (US);
Wonsuk Chang, Princeton, NJ (US);
Matthew Lloyd Childers, Medfield, MA (US);
Jared N. Cumming, Winchester, MA (US);
Jongwon Lim, Lexington, MA (US);
Min Lu, Brookline, MA (US);
Benjamin Wesley Trotter, Medfield, MA (US);
Wen-Lian Wu, Green Brook, NJ (US);
Merck Sharp & Dohme LLC, Rahway, NJ (US);
Abstract
A class of polycyclic compounds of general formula (I), wherein Base, Base, Y, Z, X, X, X, X, X, X, X, X, R, R, R, R, R, R, R, R, R, R, R, R, R, R, and Rare defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are processes for the synthesis and use of compounds.