The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2023
Filed:
Feb. 01, 2018
Applicant:
University of Massachusetts, Boston, MA (US);
Inventor:
Maolin Guo, Dartmouth, MA (US);
Assignee:
University of Massachusetts, Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2006.01); C07D 491/107 (2006.01); C07D 491/22 (2006.01); G01N 21/64 (2006.01); G01N 33/52 (2006.01);
U.S. Cl.
CPC ...
C07D 491/107 (2013.01); C07D 491/22 (2013.01); G01N 21/643 (2013.01); G01N 33/52 (2013.01);
Abstract
The present disclosure relates to compounds of Formula I, II, or III and compositions of the same, which are reversible off-on or ratiometric fluorescent iron sensors and are useful in live-cell imaging of labile iron ions and their quantification in subcellular compartments, as well as treatment of diseases associated with iron dyshomoestasis.