The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2023
Filed:
Jun. 02, 2021
Incyte Corporation, Wilmington, DE (US);
Jiacheng Zhou, Newark, DE (US);
Yingrui Dai, Wilmington, DE (US);
Zhongjiang Jia, Kennett Square, PA (US);
Yongchun Pan, Wilmington, DE (US);
James M. Parks, Newark, DE (US);
Anthony J. Tomaine, Wilmington, DE (US);
Jianji Wang, New Castle, DE (US);
Aibin Zhang, Chester Springs, PA (US);
Incyte Corporation, Wilmington, DE (US);
Abstract
The present application provides processes for preparing 4-[3-(cyanomethyl)-3-(3',5′-dimethyl-1H, 1′H-4,4′-bipyrazol-1-yl)azetidin-1-yl]-2,5-difluoro-N-[(1S)-2,2,2-trifluoro-1-methylethyl]benzamide, and phosphoric acid salt thereof, which is useful as a selective (Janus kinase 1) JAK1 inhibitor, as well as salt forms and intermediates related thereto.