The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 27, 2023

Filed:

Aug. 24, 2021
Applicant:

Know Bio, Llc, Durham, NC (US);

Inventors:

David T. Emerson, Durham, NC (US);

Michael John Bergmann, Atlanta, GA (US);

Thomas Matthew Womble, Wake Forest, NC (US);

Antony Paul Van De Ven, Nongkae, TH;

Nathan Stasko, Chapel Hill, NC (US);

F. Neal Hunter, Durham, NC (US);

Adam Cockrell, Durham, NC (US);

Rebecca Mcdonald, Chapel Hill, NC (US);

James Michael Lay, Apex, NC (US);

Assignee:

KNOW Bio, LLC, Morrisville, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 5/06 (2006.01);
U.S. Cl.
CPC ...
A61N 5/0624 (2013.01); A61N 2005/0606 (2013.01); A61N 2005/0632 (2013.01); A61N 2005/0644 (2013.01); A61N 2005/0662 (2013.01);
Abstract

Illumination devices for impinging light on tissue, for example within a body cavity of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, increasing endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and tissues with increased efficacy and reduced cytotoxicity. Particular illumination devices are disclosed that provide safe and effective treatments for upper respiratory tract infections, including coronaviridae and orthomyxoviridae.


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