The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2023
Filed:
Mar. 02, 2018
Applicant:
Loyola University Chicago, Maywood, IL (US);
Inventors:
Susan Baker, Elmhurst, IL (US);
Xufang Deng, Lyons, IL (US);
Assignee:
LOYOLA UNIVERSITY OF CHICAGO, Chicago, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/215 (2006.01); A61P 31/14 (2006.01); A61K 39/12 (2006.01); C12N 9/16 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/215 (2013.01); A61K 39/12 (2013.01); A61P 31/14 (2018.01); C12N 9/16 (2013.01); A61K 2039/5254 (2013.01); C12N 2770/20022 (2013.01); C12N 2770/20034 (2013.01);
Abstract
Coronaviruses, vaccines comprising the same, and methods for preventing disease. One embodiment of such includes a live, attenuated coronavirus comprising a variant replicase gene encoding polyproteins comprising a non-structural protein (nsp)-15, the replicase gene encoding the nsp15 and causes any change, including mutations and/or deletions, that affects the stability or activity of the nsp15.