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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11684665 B1

PDFFull Text
Date of Patent:
Jun. 27, 2023

Filed:

Dec. 22, 2016

Method for producing rna molecule compositions

Applicant:

Curevac SE, Tübingen, DE;

Inventors:

Tilmann Roos, Kusterdingen, DE;

Martin Kunze, Rottenburg, DE;

Benyamin Yazdan Panah, Tübingen, DE;

Salih Yilmaz, Biberach an der Riss, DE;

Markus Conzelmann, Tübingen, DE;

Assignee:

CureVac SE, Tübingen, DE;

Attorney:

Parker Highlander PLLC

Primary Examiner:

Antonio Galisteo Gonzalez

Int. Cl.
CPC ...
A61K 39/12 (2006.01); C12Q 1/68 (2018.01); C07K 14/005 (2006.01); C12Q 1/6844 (2018.01); A61P 21/00 (2006.01); A61P 31/00 (2006.01); A61P 39/00 (2006.01); C12N 15/10 (2006.01); C40B 40/02 (2006.01); C40B 40/08 (2006.01); A61K 39/00 (2006.01); A61K 38/00 (2006.01); C40B 10/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); A61P 21/00 (2018.01); A61P 31/00 (2018.01); A61P 39/00 (2018.01); C07K 14/005 (2013.01); C12N 15/1024 (2013.01); C12Q 1/6844 (2013.01); C40B 40/02 (2013.01); C40B 40/08 (2013.01); A61K 38/00 (2013.01); A61K 2039/53 (2013.01); A61K 2039/70 (2013.01); C12N 2760/16111 (2013.01); C12N 2760/16122 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16222 (2013.01); C12N 2760/16234 (2013.01); C40B 10/00 (2013.01); Y02A 50/30 (2018.01);
Abstract

The invention relates to a method for producing a ribonucleic acid (RNA) molecule composition comprising n different RNA molecule species, the method comprising a step of RNA in vitro transcription of a mixture of m different deoxyribonucleic acid (DNA) molecule species in a single reaction vessel in parallel, i.e. simultaneously, and a step of obtaining the RNA molecule composition. Also provided is the RNA composition provided by the inventive method and a pharmaceutical composition comprising the same as well as a pharmaceutical container. Moreover, the invention provides the RNA composition and the pharmaceutical composition for use as medicament.

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