The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2023
Filed:
Jan. 28, 2019
Applicant:
U.s. Army Research Laboratory, Adelphi, MD (US);
Inventors:
Katherine L. Akingbade, Silver Spring, MD (US);
Christian J. Sund, Bethesda, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/191 (2006.01); A61K 9/00 (2006.01); A61K 31/165 (2006.01); A61K 31/655 (2006.01);
U.S. Cl.
CPC ...
A61K 31/191 (2013.01); A61K 9/0019 (2013.01); A61K 9/0056 (2013.01); A61K 31/165 (2013.01); A61K 31/655 (2013.01);
Abstract
A method for increasing susceptibility of microorganisms to antibiotics includes providing a microorganism; administering an antibiotic including a nitro-containing amphenicol compound to the microorganism; and administering any of an uronic, aldonic, ulosonic, and aldaric feedstock to the microorganism. The feedstock is adapted to promote cell metabolism, and inhibit antibiotic inactivation pathways in the microorganism causing increased sensitivity of the microorganism to the nitro-containing amphenicol.