The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 27, 2023

Filed:

Jan. 18, 2019
Applicants:

Etherna Immunotherapies NV, Niel, BE;

Vrije Universiteit Brussel, Brussels, BE;

Inventors:

Stefaan De Koker, Niel, BE;

Sanne Bevers, Niel, BE;

Peter Tomme, Niel, BE;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 31/7105 (2006.01); A61K 38/19 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1271 (2013.01); A61K 31/7105 (2013.01); A61K 38/19 (2013.01);
Abstract

The present invention relates to the field of lipid nanoparticles (LPN); more specifically comprising an ionisable lipid, a phospholipid, a sterol, a PEG lipid and one or more nucleic acids. The LNP's of the present invention are characterized in having a minimal average diameter of about 140 nm, thereby inducing a more potent immune response. The present invention provides use of the LNPs for immunogenic delivery of nucleic acid molecules, specifically mRNA; thereby making them highly suitable for use in vaccines, such as for the treatment of cancer or infectious diseases. Finally, methods are provided for preparing such LNP's.


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De Koker, Stefaan. (2023). Lipid nanoparticles (U.S. Patent No. 11684577). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11684577

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