The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 20, 2023
Filed:
Nov. 09, 2015
Applicant:
Editas Medicine, Inc., Cambridge, MA (US);
Inventor:
Cecilia Cotta-Ramusino, Cambridge, MA (US);
Assignee:
Editas Medicine, Inc., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/64 (2006.01); C12N 15/10 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
C12N 15/64 (2013.01); C12N 9/1241 (2013.01); C12N 15/102 (2013.01); C12N 2310/122 (2013.01); C12N 2310/20 (2017.05);
Abstract
This application provides improved methods of editing the genome of a target cell. Cas9 molecules can be used to create a break in a genomic region of interest. To increase the likelihood that the break is repaired by homology-directed repair (HDR), the cell can be contacted with an HDR-enhancer. The cell may be, e.g., a human cell, a non-human animal cell, a bacterial cell, or a plant cell.