The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 20, 2023
Filed:
Sep. 01, 2016
Applicant:
Immutep S.a.s., Orsay, FR;
Inventors:
Frédéric Triebel, Versailles, FR;
Chrystelle Brignone, Chatenay-Malabry, FR;
Assignee:
IMMUTEP S.A.S., Orsay, FR;
Primary Examiner:
Int. Cl.
CPC ...
A61P 29/00 (2006.01); C07K 16/28 (2006.01); A61P 37/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2896 (2013.01); A61P 29/00 (2018.01); A61P 37/06 (2018.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01); C07K 2317/70 (2013.01); C07K 2317/73 (2013.01); C07K 2317/75 (2013.01); C07K 2317/92 (2013.01);
Abstract
Antibodies, or antigen-binding fragments thereof, that bind to Lymphocyte-activation gene-3 (LAG-3) are described, in particular antibodies, or antigen-binding fragments thereof, that are agonists of LAG-3. The antibodies bind to LAG-3 and inhibit antigen-induced CD4and/or CD8T cell proliferation, or antigen-induced CD4and/or CD8T cell activation. The antibodies may be used as medicaments, in particular for the treatment of conditions associated with proliferation and/or activation of CD4and/or CD8T cells, such as inflammatory and autoimmune disorders.