The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 20, 2023
Filed:
Aug. 31, 2020
Applicant:
Agenus Inc., Lexington, MA (US);
Inventors:
Dhan Sidhartha Chand, Woburn, MA (US);
Randi Barbara Gombos, Wilmington, MA (US);
Olga Ignatovich, Cambridge, GB;
Nicola Anne Ramsay, Cambridge, GB;
K. Mark Bushell, Saffron Walden, GB;
Emmanuel Cyrille Pascal Briend, Cambridge, GB;
Assignee:
AGENUS INC., Lexington, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61K 47/68 (2017.01); A61K 31/713 (2006.01); C12N 15/63 (2006.01); C12N 5/10 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 31/713 (2013.01); A61K 39/001129 (2018.08); A61K 47/6803 (2017.08); A61K 47/6849 (2017.08); C12N 5/10 (2013.01); C12N 15/63 (2013.01); A61K 45/06 (2013.01); A61K 2039/507 (2013.01); C07K 2317/21 (2013.01); C07K 2317/31 (2013.01); C07K 2317/565 (2013.01);
Abstract
The instant disclosure provides antibodies that specifically bind to CD96 (e.g., human CD96) and antagonize CD96 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.