The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 20, 2023
Filed:
Feb. 21, 2019
Applicant:
The University of Chicago, Chicago, IL (US);
Inventors:
Assignee:
The University of Chicago, Chicago, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/78 (2006.01); C40B 40/10 (2006.01);
U.S. Cl.
CPC ...
C07K 14/78 (2013.01); C40B 40/10 (2013.01);
Abstract
The current application describes various compositions and methods for the production of FN3-based binding proteins with improved stability properties. Aspects of the disclosure relate to polypeptides comprising a variant fibronectin type III (FN3) domain fromorcomprising one or more amino acid substitutions or insertions in a loop region of FN3, in a non-loop region of FN3, or in both.