The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 20, 2023

Filed:

Jan. 21, 2020
Applicant:

Receptos Llc, New York, NY (US);

Inventors:

Minhua Chen, Suzhou, CN;

Xiaoyu Zhang, Suzhou, CN;

Yanfeng Zhang, Suzhou, CN;

Chaohui Yang, Suzhou, CN;

Xiaoting Zhai, Suzhou, CN;

Kaiqiang Yan, Suzhou, CN;

Assignee:

RECEPTOS LLC, New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 271/06 (2006.01);
U.S. Cl.
CPC ...
C07D 271/06 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present disclosure is directed to novel crystalline forms of ozanimod and ozanimod hydrochloride, as well as preparation method thereof. Said crystalline forms of ozanimod and ozanimod hydrochloride can be used for treating autoimmune diseases, particularly used for preparing drugs for treating multiple sclerosis and ulcerative colitis. The crystalline forms of the present disclosure have one or more advantages in solubility, melting point, stability, dissolution, bioavailability and processability and provide new and better choices for the preparation of ozanimod drug product, and are very valuable for drug development.


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