The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 20, 2023

Filed:

Jun. 17, 2021
Applicant:

Landos Biopharma, Inc., Blacksburg, VA (US);

Inventors:

Josep Bassaganya-Riera, Blacksburg, VA (US);

Andrew Leber, Blacksburg, VA (US);

Raquel Hontecillas, Blacksburg, VA (US);

Assignee:

LANDOS BIOPHARMA, INC., Blacksburg, VA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 211/04 (2006.01); A61K 31/4427 (2006.01); A61P 3/10 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); C07D 239/34 (2006.01); A61P 31/12 (2006.01); A61P 31/04 (2006.01); A61P 1/04 (2006.01);
U.S. Cl.
CPC ...
C07D 211/04 (2013.01); A61P 1/04 (2018.01); A61P 3/10 (2018.01); A61P 29/00 (2018.01); A61P 31/04 (2018.01); A61P 31/12 (2018.01); A61P 35/00 (2018.01); C07D 239/34 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01);
Abstract

Provided are compounds that target the nucleotide-binding oligomerization domain, leucine rich repeat containing X1 (NLRX1) pathway. The compounds can be used to treat multiple conditions, including inflammatory, immune-mediated, and/or chronic inflammatory gastrointestinal diseases; systemic immune-mediated diseases; cancers; and infectious diseases.


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