The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 20, 2023
Filed:
Apr. 15, 2019
Applicant:
Precision Nanosystems Ulc, Vancouver, CA;
Inventors:
Anitha Thomas, New Westminster, CA;
Andrew William Brown, Vancouver, CA;
Rebecca Anne Grace De Souza, Vancouver, CA;
Tara L. Fernandez, Vancouver, CA;
Assignee:
Precision Nanosystems ULC, Vancouver, CA;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/28 (2006.01); A61K 47/26 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/28 (2013.01); A61K 47/26 (2013.01); A61K 48/0008 (2013.01);
Abstract
A reagent composition for delivery nucleic acid therapeutics to cells is provided. The reagent includes ionizable lipid, structural lipid, and a stabilizing agent which improves the transfection efficiency of nucleic acids, and leaves transfected cells viable. The 5 transfection reagent is effective in plasmid and mRNA delivery, and in neurons and progenitor-like cells. It may be used for ex vivo cell therapy.