The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 20, 2023

Filed:

Apr. 26, 2019
Applicant:

University of North Texas Health Science Center, Fort Worth, TX (US);

Inventors:

Tasneem Putliwala Sharma, Fort Worth, TX (US);

Colleen Mary McDowell, Fort Worth, TX (US);

Abbot Frederick Clark, Fort Worth, TX (US);

Husain Lohawala, Fort Worth, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 1/02 (2006.01); B01L 3/00 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A01N 1/0247 (2013.01); B01L 3/502 (2013.01); G01N 33/5088 (2013.01); B01L 2300/042 (2013.01); B01L 2300/0609 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0809 (2013.01); B01L 2300/0832 (2013.01); B01L 2300/0858 (2013.01); B01L 2300/14 (2013.01); B01L 2400/0487 (2013.01);
Abstract

The present disclosure relates to devices, systems, and methods for modeling ocular translaminar pressure gradients ex vivo. A first fluid pressure level can be applied to a first side of a wall of donor eye cup (e.g., a posterior human eye cup) to simulate intracranial pressure (ICP), for example around the optical nerve head (ONH), and a second fluid pressure level can be applied to a second side of the wall of the donor eye cup to simulate intraocular pressure (IOP). These devices, systems, and methods are unique in that they allow ex vivo modeling of dynamic changes in translaminar pressure gradients.


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