The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2023

Filed:

Jan. 23, 2020
Applicants:

Bipin Gupta, Pleasanton, CA (US);

Marc Key, Ojai, CA (US);

Inventors:

Bipin Gupta, Pleasanton, CA (US);

Marc Key, Ojai, CA (US);

Assignees:

Diagnostic BioSystems, Pleasanton, CA (US);

Other;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 1/30 (2006.01); G01N 1/28 (2006.01); G01N 33/483 (2006.01); G01N 1/44 (2006.01); C08G 65/332 (2006.01); G01N 1/42 (2006.01); C09D 171/02 (2006.01); C09D 129/04 (2006.01); C09D 105/04 (2006.01); G02B 21/34 (2006.01); C08L 71/02 (2006.01); C08L 29/04 (2006.01);
U.S. Cl.
CPC ...
G01N 1/30 (2013.01); C08G 65/3326 (2013.01); C08L 29/04 (2013.01); C08L 71/02 (2013.01); C09D 105/04 (2013.01); C09D 129/04 (2013.01); C09D 171/02 (2013.01); G01N 1/28 (2013.01); G01N 1/2813 (2013.01); G01N 1/42 (2013.01); G01N 1/44 (2013.01); G01N 33/4833 (2013.01); G01N 2001/302 (2013.01); G02B 21/34 (2013.01);
Abstract

A sample protection method is provided which may be used for protecting a biological sample on a microscope slide, such as during heat-induced target retrieval and/or after heat-induced target retrieval such that: 1) the sample remains adherent to the microscope slide; and 2) the microscopic morphology of the biological sample remains intact. In some embodiments, the sample protection method may include the steps of: creating a sectioned sample that is in contact with a microscope slide; applying a protecting reagent onto a sectioned sample that is in contact with a microscope slide and drying the protecting reagent in which the protecting reagent may be both applied and dried onto the sectioned sample before and/or after performing target retrieval on the sectioned sample. The protecting reagent may include a water-soluble polymer and/or a water-soluble wax, such as polyethylene glycol, polypropylene glycol, polyvinyl alcohol, polyvinylpyrrolidone, alginic acid, and carrageenan.


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