The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2023
Filed:
Mar. 03, 2014
Applicant:
Hoffmann-la Roche Inc., Nutley, NJ (US);
Inventors:
Silke Hansen, Iffeldorf, DE;
Klaus-Peter Kuenkele, Benediktbeuern, DE;
Dietmar Reusch, Munich, DE;
Ralf Schumacher, Penzberg, DE;
Assignee:
Hoffmann-La Roche Inc., Nutley, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2863 (2013.01); C07K 16/00 (2013.01); C07K 2317/41 (2013.01); C07K 2317/52 (2013.01);
Abstract
The invention provides an antibody comprising human IgG1 or IgG3 heavy chain constant domains that are glycosylated with a sugar chain at Asn297, said antibody being characterized in that the amount of fucose within said sugar chain is at least 99%, and in addition the amount of NGNA is 1% or less and/or the amount of N-terminal alpha 1,3 galactose is 1% or less, and uses thereof.