The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2023

Filed:

Mar. 10, 2016
Applicants:

Eureka Therapeutics, Inc., Emeryville, CA (US);

Memorial Sloan-kettering Cancer Center, New York, NY (US);

Inventors:

Cheng Liu, Oakland, CA (US);

Su Yan, State College, PA (US);

Pei Wang, Union City, CA (US);

Nai-Kong Cheung, Purchase, NY (US);

Hongfen Guo, Forest Hills, NY (US);

Ming Cheng, Roosevelt Island, NY (US);

Assignee:

Eureka Therapeutics, Inc., Emeryville, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); C07K 16/28 (2006.01); A61K 47/68 (2017.01); C07K 16/22 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2857 (2013.01); A61K 47/6891 (2017.08); C07K 16/22 (2013.01); C07K 16/2803 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/31 (2013.01); C07K 2317/34 (2013.01); C07K 2317/622 (2013.01); C07K 2317/732 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

The invention relates to antibodies, and in particular, to antibodies exhibiting specificity for Receptor tyrosine kinase-like Orphan Receptors (ROR), and to uses thereof for example in the treatment of cancer. The invention extends to polynucleotide and polypeptide sequences encoding the antibodies, and therapeutic uses thereof, and to diagnostic kits comprising these molecules. The invention also extends to antibody-drug conjugates and to uses thereof in therapy.


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