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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11673947 B1

PDFFull Text
Date of Patent:
Jun. 13, 2023

Filed:

Aug. 13, 2019

Target tissue-specific antigen-binding molecule

Applicant:

Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;

Inventors:

Tomoyuki Igawa, Shizuoka, JP;

Shigero Tamba, Shizuoka, JP;

Kanako Tatsumi, Shizuoka, JP;

Shun Shimizu, Shizuoka, JP;

Shojiro Kadono, Kanagawa, JP;

Assignee:

Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;

Attorney:

Fish & Richardson P.C.

Primary Examiner:

Jessica H Roark

Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/24 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); C07K 16/44 (2006.01); G01N 33/68 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/248 (2013.01); C07K 16/00 (2013.01); C07K 16/005 (2013.01); C07K 16/18 (2013.01); C07K 16/2866 (2013.01); C07K 16/30 (2013.01); C07K 16/44 (2013.01); G01N 33/6845 (2013.01); G01N 33/6869 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/34 (2013.01); C07K 2317/55 (2013.01); C07K 2317/732 (2013.01); C07K 2317/92 (2013.01); G01N 2333/5412 (2013.01); G01N 2500/00 (2013.01); G01N 2500/20 (2013.01);
Abstract

The present inventors discovered that problems of existing antibody pharmaceuticals can be solved by producing antigen-binding molecules that contain an antigen-binding domain whose antigen-binding activity varies depending on the concentration of a target tissue-specific compound. Use of antigen-binding molecules of the present invention enables various diseases that originate from a target tissue to be treated in a manner specific to the target tissue.

Find Patent Forward Citations

Igawa, Tomoyuki. (2023). Target tissue-specific antigen-binding molecule (U.S. Patent No. 11673947). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11673947

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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