The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2023
Filed:
Dec. 20, 2017
Japan Tobacco Inc., Tokyo, JP;
Leo Pharma A/s, Ballerup, DK;
Hiromu Takiguchi, Takatsuki, JP;
Akinobu Higashi, Takatsuki, JP;
Takashi Inaba, Takatsuki, JP;
Takashi Watanabe, Takatsuki, JP;
Tsubasa Takeichi, Takatsuki, JP;
Anders Klarskov Petersen, Ballerup, DK;
Per Vedsoe, Ballerup, DK;
Kim Lebek Jensen, Ballerup, DK;
Jan Bornholdt, Ballerup, DK;
Soren Ebdrup, Ballerup, DK;
Japan Tobacco Inc., Tokyo, JP;
LEO Pharma A/S, Ballerup, DK;
Abstract
The present invention provides processes for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives, which are useful as a Janus kinase (JAK) inhibitor, intermediates thereof, and processes for preparing the intermediates. The present invention provides processes for preparing 3-[(3S,4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile using salts of (3S,4R)-1-benzyl-3-methyl-1,6-diazaspiro[3.4]octane with organic acids.