The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2023

Filed:

Mar. 30, 2021
Applicant:

Theravance Biopharma R&d Ip, Llc, South San Francisco, CA (US);

Inventors:

Mandy Loo, San Jose, CA (US);

Svitlana Kulyk, Redwood City, CA (US);

Christopher Bailey, Mountain View, CA (US);

Jennifer Kozak, Pacifica, CA (US);

Matthew B. Soellner, Ann Arbor, MI (US);

Adam D. Hughes, Half Moon Bay, CA (US);

Assignee:

Theravance Biopharma R&D IP, LLC, South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/506 (2006.01); A61K 9/12 (2006.01); A61P 1/16 (2006.01); A61P 9/00 (2006.01); A61P 11/00 (2006.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 9/008 (2013.01); A61K 9/0075 (2013.01); A61K 9/0078 (2013.01); A61K 45/06 (2013.01); A61P 1/16 (2018.01); A61P 9/00 (2018.01); A61P 11/00 (2018.01); A61P 35/00 (2018.01); A61K 31/506 (2013.01);
Abstract

The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5.


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