IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11673878 B1

PDFFull Text
Date of Patent:
Jun. 13, 2023

Filed:

Nov. 24, 2020

Benzazepine derivatives

Applicant:

Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;

Inventors:

Keizo Kan, Osaka, JP;

Masatoshi Takuwa, Osaka, JP;

Hirotaka Tanaka, Osaka, JP;

Hideto Fujiwara, Osaka, JP;

Hokuto Yamabe, Osaka, JP;

Satoshi Matsuda, Osaka, JP;

Kazuhiro Ohdachi, Osaka, JP;

Taiki Hanari, Osaka, JP;

Yasuhiro Menjo, Osaka, JP;

Tatsuya Urushima, Osaka, JP;

Shigekazu Fujita, Osaka, JP;

Assignee:

OTSUKA PHARMACEUTICAL CO., LTD., Tokyo, JP;

Attorney:

Sughrue Mion, PLLC

Primary Examiner:

Brenda L Coleman

Int. Cl.
CPC ...
C07D 223/16 (2006.01); C07D 401/06 (2006.01); C07D 401/10 (2006.01); C07D 401/14 (2006.01); C07D 403/06 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); A61K 31/55 (2006.01); A61P 13/12 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 401/10 (2013.01); C07D 403/06 (2013.01); C07D 223/16 (2013.01);
Abstract

The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin Vand Vantagonisms, and medical uses thereof. In the formula, Ris optionally substituted Calkyl, etc.; L is —C(═O)—NH—, etc.; Ring Ais a hydrocarbon ring, etc.; Ring Ais a hydrocarbon ring, etc.; and each of Rings Aand Amay have at least one substituent.

Find Patent Forward Citations

Loading…