The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2023
Filed:
Nov. 23, 2020
Applicant:
North Carolina State University, Raleigh, NC (US);
Inventors:
Joshua G. Pierce, Raleigh, NC (US);
Jonathan J. Mills, Raleigh, NC (US);
Assignee:
North Carolina State University, Raleigh, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 263/40 (2006.01); C07D 263/46 (2006.01); A61P 31/04 (2006.01); A01N 43/76 (2006.01); A61L 31/16 (2006.01); A61L 29/16 (2006.01); A61L 27/54 (2006.01); A61L 31/08 (2006.01);
U.S. Cl.
CPC ...
C07D 263/40 (2013.01); A01N 43/76 (2013.01); A61L 27/54 (2013.01); A61L 29/16 (2013.01); A61L 31/08 (2013.01); A61L 31/16 (2013.01); A61P 31/04 (2018.01); C07D 263/46 (2013.01); A61L 2300/204 (2013.01); A61L 2300/404 (2013.01);
Abstract
Provided herein are oxazolidinone derivatives that can exhibit anti-microbial activity and/or activity as biofilm modulating agents (e.g., activity as biofilm inhibitors and/or activity as biofilm dispersal agents). The compounds can exhibit potent activity anti-microbial activity (e.g., potent activity against Gram-positive positive bacteria including methicillin-resistant). The compounds can exhibit potent activity against biofilms. In some cases, the compounds can exhibit both anti-microbial activity and biofilm modulation properties.