The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2023

Filed:

May. 23, 2019
Applicants:

The Board of Trustees of the University of Illinois, Urbana, IL (US);

The Regents of the University of California, Oakland, CA (US);

Inventors:

John A. Katzenellenbogen, Urbana, IL (US);

Seema K. Tiwari-Woodruff, Riverside, CA (US);

Sung Hoon Kim, Champaign, IL (US);

Benita Katzenellenbogen, Urbana, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/56 (2006.01); C07D 409/04 (2006.01); C07D 409/10 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
C07D 231/56 (2013.01); A61P 25/28 (2018.01); C07D 409/04 (2013.01); C07D 409/10 (2013.01);
Abstract

4-Hydroxyphenyl-2H-indazol-5-ol compounds are estrogen receptor beta ligands that have immunomodulatory properties and increase oligodendrocyte survival, differentiation, and remyelination. The compounds, compositions, and kits are useful in the treatment of multiple sclerosis and endometriosis.


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